1-Bromobutane has three main uses. First, it is a raw material for organic synthesis. It can be obtained by substitution reaction to obtain butanol; after elimination reaction, butene is produced. This is of great significance in the synthesis of drugs, fragrances, dyes, etc. If a certain drug is prepared, 1-bromobutane is used as the key intermediate, and after a series of reactions, it becomes the desired active ingredient. Second, it is a solvent. Because of its good solubility, in the organic reaction system, the reactants are evenly mixed to improve the reaction rate and yield. In the production of some coatings and adhesives, 1-bromobutane is used as a solvent to help the components disperse evenly to ensure product quality. Third, it is used in alkylation reagents. In organic synthesis, butyl can be introduced into specific compounds to change their properties and functions. In the preparation of surfactants, 1-bromobutane participates in the alkylation reaction, giving the surfactant specific properties. In short, 1-bromobutane has a wide range of uses and plays a key role in the fields of organic synthesis, solvents and alkylation.

1-Bromobutane, also known as n-butyl bromide, is an organic compound. It has the following physical properties:
Looking at it, 1-bromobutane is a colorless and transparent liquid. When pure, it is clear and has no variegated color. Under normal conditions, it is in a flowing state.
Smell it, it has a specific smell. This smell is non-fragrant and non-odorous. It is quite unique, but it does not have a strong irritating smell.
Measure its density, which is heavier than water, about 1.2758g/cm ³. If it is placed in one place with water, it can be seen that it sinks to the bottom of the water.
Measure its boiling point, which is about 101.6 ° C. Under normal pressure, when heated to this temperature, 1-bromobutane will change from liquid to gaseous state.
In terms of its melting point, it is about -112.4 ° C. When the temperature drops below this point, 1-bromobutane will condense into a solid state.
In terms of solubility, 1-bromobutane is insoluble in water, but it can be miscible with organic solvents such as ethanol, ether, and chloroform. This is due to its molecular structure characteristics. It is quite different from the polarity of water, but it is similar to the polarity of organic solvents and follows the principle of similar compatibility.

1-Bromobutane is an organic compound with interesting chemical properties. This compound has the generality of halogenated alkanes and can participate in many chemical reactions.
The first one to bear the brunt is the nucleophilic substitution reaction. Due to the strong electronegativity of bromine atoms, the electron cloud in the C-Br bond is biased towards bromine, and the carbon is partially positively charged, which is vulnerable to attack by nucleophilic reagents. For example, when co-heated with an aqueous solution of sodium hydroxide, the hydroxyl group acts as a nucleophilic reagent to replace the bromine atom to generate 1-butanol. This is a common method for preparing alcohols. The reaction is: "CH 🥰 CH 🥰 CH 🥰 CH 🥰 CH 🥰 Br + NaOH → CH 🥰 CH 🥰 CH 🥰 OH + NaBr".
Furthermore, 1-bromobutane can be eliminated. By co-heating an alcoholic solution of potassium hydroxide, the bromine atom and the hydrogen atom on the adjacent carbon will be removed in the form of hydrogen bromide to form butene. This reaction follows the Zaitsev rule, that is, the main formation of olefins with multiple hydrocarbon groups attached to the double-bonded carbon atoms. The reaction formula is: "CH 🥰 CH 🥰 CH 🥰 Br + KOH (alcohol) → CH 🥰 CH 🥰 CH = CH 🥰 + KBr + H 🥰 O".
In addition, 1-bromobutane can still interact with metal magnesium to form Grignard reagents in an anhydrous ether environment. This Grignard reagent is extremely reactive and can react with many carbonyl-containing compounds. It is used in the field of organic synthesis to form carbon-carbon bonds, which is of great significance. For example, by reacting with formaldehyde, an alcohol with one more carbon atom than the original halogenated hydrocarbon can be finally generated. The rich and diverse chemical properties of
1-bromobutane, including nucleophilic substitution, elimination and metal reaction, make it play a key role in the stage of organic synthesis and provide an important way for the preparation of various organic compounds.

The method of preparing 1-bromobutane is based on the reaction of n-butanol with hydrobromic acid. The details are as follows:
First take an appropriate amount of n-butanol and place it in a round-bottomed flask. Hydrobromic acid is also prepared and slowly poured into the flask, and the two are mixed. In order to promote the speed of the reaction and make the reaction uniform, a little sulfuric acid is often added as a catalyst. The properties of sulfuric acid can increase the activity of hydrobromic acid, making the reaction easy to occur.
Then, a reflux condensation device is connected to the flask. The essence of this device is to make the steam generated during the reaction process cool and return to the liquid, and flow back into the flask to avoid the escape of the reactants and the reduction of the yield. The device is established, and the flask is heated slowly. When heating, pay attention to the control of temperature, do not make it too high or too low. If the temperature is too high, side reactions will be easy to occur; if it is too low, the reaction will be slow.
At the appropriate temperature, n-butanol reacts with hydrobromic acid. The hydroxyl group of n-butanol is replaced by a bromine atom to produce 1-bromobutane. After the reaction is completed, when it is slightly cold, the reaction liquid is moved into the separation funnel. Because 1-bromobutane is immiscible with water and unreacted substances, and the density is different, it can be separated by the method of liquid separation.
After separation, 1-bromobutane may contain impurities. It needs to be washed with water and dried with a desiccant to remove the moisture. Finally, pure 1-bromobutane can be obtained by distillation. When distilled, the fraction with a specific boiling point is collected, which is 1-bromobutane. This is the usual method for making 1-bromobutane.

1-Bromobutane is also a chemical substance. During storage and transportation, many matters cannot be ignored.
First, pay attention to its storage environment. 1-Bromobutane is volatile and flammable, so it should be stored in a cool and ventilated warehouse. The temperature of the warehouse should not be too high, and it should be controlled within a specific range to prevent its volatilization from intensifying or causing danger due to excessive temperature. And it must be kept away from fire and heat sources, and fireworks are strictly prohibited. This is the priority of safety.
Second, packaging is also the key. The packaging materials used must be well sealed to prevent 1-bromobutane from escaping. The packaging material should be sturdy and durable enough to withstand the vibration and collision that may be encountered during transportation, so as not to damage and leak.
Third, when transporting, there are also many precautions. The transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. During driving, ensure that the container does not leak, collapse, fall, or damage. The tank (tank) car used during transportation should have a grounding chain, and holes can be set in the tank to reduce shock and generate static electricity. And it should not be mixed with oxidants, alkalis, etc., because of its chemical properties, contact with these substances, or cause violent reactions, resulting in disasters.
Fourth, the operator also needs to have professional knowledge and skills. Whether it is the daily management during storage or the operation during transportation, the operating procedures should be strictly followed, and no negligence should be allowed, so as to ensure the safety of 1-bromobutane during storage and transportation.